Fake Sports, Real Impact? Investigating Social Identity, Identity Construction, and Perceptions of Self Using Fantasy Sports Leagues as a Platform for Communication Research

The present study used fantasy sports as a vehicle for investigating social identity formation and expression in online communication scenarios. Particularly of interest to the researcher were the mechanisms by which affinity for an individual’s fantasy sports league was generated, perceived public commitment to a fantasy sports identity, and the impact that commitment had on respondents’ behavior and self-concept. It was believed completing tasks associate with fantasy sports competitions and interacting socially with fellow fantasy league participants would have a direct effect on players’ level of collective self-esteem. It was also posited evaluations of collective self-esteem would then predict the likelihood of and extent to which players publicly committed themselves to fantasy sports as part of their identity. Recent research in the field of computer-mediated communication has investigated the effects of perceived public commitment to a personal identity trait. Building on such research, the present study looked to document the effect of public commitment to a group based, social identity. In sum, a total of five hypotheses were proposed predicting various relationships among variables including collective self-esteem, public commitment, prototypical behavioral displays, and personal self-esteem. Survey data was collected and used to test each hypothesis. The majority of hypothesized relationships were supported. The implication of these findings and their impact on the fields of communication, fantasy sports, psychology, and sociology are discussed here

The role of the amygdala during emotional processing in Huntington's disease: from pre-manifest to late stage disease.

BACKGROUND: Deficits in emotional processing can be detected in the pre-manifest stage of Huntington's disease and negative emotion recognition has been identified as a predictor of clinical diagnosis. The underlying neuropathological correlates of such deficits are typically established using correlative structural MRI studies. This approach does not take into consideration the impact of disruption to the complex interactions between multiple brain circuits on emotional processing. Therefore, exploration of the neural substrates of emotional processing in pre-manifest HD using fMRI connectivity analysis may be a useful way of evaluating the way brain regions interrelate in the period prior to diagnosis. METHODS: We investigated the impact of predicted time to disease onset on brain activation when participants were exposed to pictures of faces with angry and neutral expressions, in 20 pre-manifest HD gene carriers and 23 healthy controls. On the basis of the results of this initial study went on to look at amygdala dependent cognitive performance in 79 Huntington's disease patients from a cross-section of disease stages (pre-manifest to late disease) and 26 healthy controls, using a validated theory of mind task: "the Reading the Mind in the Eyes Test" which has been previously been shown to be amygdala dependent. RESULTS: Psychophysiological interaction analysis identified reduced connectivity between the left amygdala and right fusiform facial area in pre-manifest HD gene carriers compared to controls when viewing angry compared to neutral faces. Change in PPI connectivity scores correlated with predicted time to disease onset (r=0.45, p<0.05). Furthermore, performance on the "Reading the Mind in the Eyes Test" correlated negatively with proximity to disease onset and became progressively worse with each stage of disease. CONCLUSION: Abnormalities in the neural networks underlying social cognition and emotional processing can be detected prior to clinical diagnosis in Huntington's disease. Connectivity between the amygdala and other brain regions is impacted by the disease process in pre-manifest HD and may therefore be a useful way of identifying participants who are approaching a clinical diagnosis. Furthermore, the "Reading the Mind in the Eyes Test" is a surrogate measure of amygdala function that is clinically useful across the entire cross-section of disease stages in HD.The work included in this manuscript has been partially funded by financial support from the NIHR Cambridge Biomedical Research Centre and the Cambridge University NHS Foundation Trust. JBR is supported by the Wellcome Trust (088324).This is the final version of the article. It first appeared at http://dx.doi.org/10.1016/j.neuropsychologia.2015.02.01

Electrical Components for Marine Renewable Energy Arrays: A Techno-Economic Review

This paper presents a review of the main electrical components that are expected to be present in marine renewable energy arrays. The review is put in context by appraising the current needs of the industry and identifying the key components required in both device and array-scale developments. For each component, electrical, mechanical and cost considerations are discussed; with quantitative data collected during the review made freely available for use by the community via an open access online repository. This data collection updates previous research and addresses gaps specific to emerging offshore technologies, such as marine and floating wind, and provides a comprehensive resource for the techno-economic assessment of offshore energy arrays

CARMA Measurements of the Sunyaev-Zel'dovich Effect in RXJ1347.5-1145

We demonstrate the Sunyaev-Zel'dovich (SZ) effect imaging capabilities of the Combined Array for Research in Millimeter-wave Astronomy (CARMA) by presenting an SZ map of the galaxy cluster RXJ1347.5-1145. By combining data from multiple CARMA bands and configurations, we are able to capture the structure of this cluster over a wide range of angular scales, from its bulk properties to its core morphology. We find that roughly 9% of this cluster's thermal energy is associated with sub-arcminute-scale structure imparted by a merger, illustrating the value of high-resolution SZ measurements for pursuing cluster astrophysics and for understanding the scatter in SZ scaling relations. We also find that the cluster's SZ signal is lower in amplitude than suggested by a spherically-symmetric model derived from X-ray data, consistent with compression along the line of sight relative to the plane of the sky. Finally, we discuss the impact of upgrades currently in progress that will further enhance CARMA's power as an SZ imaging instrument.Comment: 8 pages, 6 figure

Constraining the Physical Properties of Stellar Coronal Mass Ejections with Coronal Dimming: Application to Far Ultraviolet Data of ϵ\epsilon Eridani

Coronal mass ejections (CMEs) are a prominent contributor to solar system space weather and might have impacted the Sun's early angular momentum evolution. A signal diagnostic of CMEs on the Sun is coronal dimming: a drop in coronal emission, tied to the mass of the CME, that is the direct result of removing emitting plasma from the corona. We present the results of a coronal dimming analysis of Fe XII 1349 A and Fe XXI 1354 A emission from $\epsilon$ Eridani ($\epsilon$ Eri), a young K2 dwarf, with archival far-ultraviolet observations by the Hubble Space Telescope's Cosmic Origins Spectrograph. Following a flare in February 2015, $\epsilon$ Eri's Fe XXI emission declined by $81\pm5$%. Although enticing, a scant 3.8 min of preflare observations allows for the possibility that the Fe XXI decline was the decay of an earlier, unseen flare. Dimming nondetections following each of three prominent flares constrain the possible mass of ejected Fe XII-emitting (1 MK) plasma to less than a few $\times10^{15}$ g. This implies that CMEs ejecting this much or more 1 MK plasma occur less than a few times per day on $\epsilon$ Eri. On the Sun, $10^{15}$ g CMEs occur once every few days. For $\epsilon$ Eri, the mass loss rate due to CME-ejected 1 MK plasma could be $<0.6$ $\dot{M}_\odot$, well below the star's estimated 30 $\dot{M}_\odot$ mass loss rate (wind + CMEs). The order-of-magnitude formalism we developed for these mass estimates can be broadly applied to coronal dimming observations of any star.Comment: 27 pages, 22 figures, accepted to Ap

Genetic Determinants of Lipids and Cardiovascular Disease Outcomes: A Wide-Angled Mendelian Randomization Investigation.

BACKGROUND: Evidence from randomized trials has shown that therapies that lower LDL (low-density lipoprotein)-cholesterol and triglycerides reduce coronary artery disease (CAD) risk. However, there is still uncertainty about their effects on other cardiovascular outcomes. We therefore performed a systematic investigation of causal relationships between circulating lipids and cardiovascular outcomes using a Mendelian randomization approach. METHODS: In the primary analysis, we performed 2-sample multivariable Mendelian randomization using data from participants of European ancestry. We also conducted univariable analyses using inverse-variance weighted and robust methods, and gene-specific analyses using variants that can be considered as proxies for specific lipid-lowering medications. We obtained associations with lipid fractions from the Global Lipids Genetics Consortium, a meta-analysis of 188 577 participants, and genetic associations with cardiovascular outcomes from 367 703 participants in UK Biobank. RESULTS: For LDL-cholesterol, in addition to the expected positive associations with CAD risk (odds ratio [OR] per 1 SD increase, 1.45 [95% CI, 1.35-1.57]) and other atheromatous outcomes (ischemic cerebrovascular disease and peripheral vascular disease), we found independent associations of genetically predicted LDL-cholesterol with abdominal aortic aneurysm (OR, 1.75 [95% CI, 1.40-2.17]) and aortic valve stenosis (OR, 1.46 [95% CI, 1.25-1.70]). Genetically predicted triglyceride levels were positively associated with CAD (OR, 1.25 [95% CI, 1.12-1.40]), aortic valve stenosis (OR, 1.29 [95% CI, 1.04-1.61]), and hypertension (OR, 1.17 [95% CI, 1.07-1.27]), but inversely associated with venous thromboembolism (OR, 0.79 [95% CI, 0.67-0.93]) and hemorrhagic stroke (OR, 0.78 [95% CI, 0.62-0.98]). We also found positive associations of genetically predicted LDL-cholesterol and triglycerides with heart failure that appeared to be mediated by CAD. CONCLUSIONS: Lowering LDL-cholesterol is likely to prevent abdominal aortic aneurysm and aortic stenosis, in addition to CAD and other atheromatous cardiovascular outcomes. Lowering triglycerides is likely to prevent CAD and aortic valve stenosis but may increase thromboembolic risk

The SSTARS (STeroids and Stents Against Re-Stenosis) Trial : different stent alloys and the use of peri-procedural oral corticosteroids to prevent in-segment restenosis after percutaneous coronary intervention

Background Stent design and technological modifications to allow for anti-proliferative drug elution influence restenosis rates following percutaneous coronary intervention (PCI). We aimed to investigate whether peri-procedural administration of corticosteroids or the use of thinner strut cobalt alloy stents would reduce rates of binary angiographic restenosis (BAR) after PCI. Methods This was a two centre, mixed single and double blinded, randomised controlled trial using a factorial design. We compared (a) the use of prednisolone to placebo, starting at least six hours pre-PCI and continued for 28 days post-PCI, and (b) cobalt chromium (CoCr) to stainless steel (SS) alloy stents, in patients admitted for PCI. The primary end-point was BAR at six months. Results 315 patients (359 lesions) were randomly assigned to either placebo (n = 145) or prednisolone (n = 170) and SS (n = 160) or CoCr (n = 160). The majority (58%) presented with an ACS, 11% had diabetes and 287 (91%) completed angiographic follow up. BAR occurred in 26 cases in the placebo group (19.7%) versus 31 cases in the prednisolone group (20.0%) respectively, p = 1.00. For the comparison between SS and CoCr stents, BAR occurred in 32 patients (21.6%) versus 25 patients (18.0%) respectively, p = 0.46. Conclusion Our study showed that treating patients with a moderately high dose of prednisolone for 28 days following PCI with BMS did not reduce the incidence of BAR. In addition, we showed no significant reduction in 6 month restenosis rates with stents composed of CoCr alloy compared to SS